asked

Can high anti-saccharomyces cerevisiae antibodies (ASCA) in the blood mean anything besides Crohn's disease and Ulcerative Colitis? I do not have Celiac disease, and all related blood tests are negative. I have had stomach aches, diarrhea, eruptive vellus hair cysts, and ganglion cysts since I was 11, which were diagnosed as IBS. These symptoms improve with a strict diet excluding gluten, wheat, yeast, and sugar. Is high ASCA enough for a diagnosis of Crohn's, and is a colonoscopy necessary if dietary changes manage the symptoms?

March 19th, 2023

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