asked

My daughter is 52 and was recently diagnosed with early-stage invasive lobular carcinoma in her right breast. The biopsy report indicates a Nottingham grade 1, with 10% of cells showing intercellular cytoplasmic vacuoles, strong AE1/AE3 cytokeratin positivity, aberrant E-cadherin expression, positive estrogen receptors, and negative progesterone receptors. No lymphovascular invasion is seen, and HER2 testing is pending. She is considering a double mastectomy with breast plastic reconstruction and is scared of chemotherapy. Can radiation be an alternative, and is there a high chance of cancer recurrence due to her hormone receptor status?

June 20th, 2023

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